coleman組織表面灌注系統(tǒng)

灌注系統(tǒng)概述

HSE—HA生理學(xué)系統(tǒng)是一系列應(yīng)用廣泛的完備產(chǎn)品，可用于整體動(dòng)物生理學(xué)、立體或在體器官和組織灌注及組織浴槽研究。這些系統(tǒng)具有廣泛的應(yīng)用，包括傳統(tǒng)的安全藥理學(xué)、DMPK、毒理學(xué)、呼吸系統(tǒng)、心臟病學(xué)、分子生物學(xué)和生理學(xué)。每個(gè)系統(tǒng)都設(shè)計(jì)了標(biāo)準(zhǔn)的組件，再加一些其他配置以適合特殊研究的需要。。標(biāo)注組件也意味著如果你是需要將現(xiàn)有設(shè)備配齊，或者進(jìn)行系統(tǒng)升級(jí)，或者是完整的配套產(chǎn)品，你都只需要購(gòu)買(mǎi)需要的構(gòu)件。HSE-HA生理學(xué)系統(tǒng)為你提供各種工具，使你的研究走向多產(chǎn)和成功。

我們提供大多數(shù)生理學(xué)檢測(cè)設(shè)備，包括放大器、電極、傳感器和電化學(xué)檢測(cè)器。參數(shù)包括力、位移、壓力、液體和氣體流、心電圖(單導(dǎo)聯(lián)—12導(dǎo)聯(lián)系統(tǒng))、MAP(單個(gè)或多個(gè)部位)、腦電圖、肌電圖、連續(xù)支流灌注傳統(tǒng)的血?dú)鈪?shù)和電解質(zhì)的分析，可以選擇程序化軟件和傳統(tǒng)的刺激器作為放大器、電極和傳感器等產(chǎn)品的補(bǔ)充。

HSE-DAQ系統(tǒng)產(chǎn)品家族(BDAS、ACAD、HAEMODYN、ISOHEART、PULMODYN、PENNOCK)可以記錄你的初始信號(hào)，計(jì)算到處的參數(shù)，注釋數(shù)據(jù)，快速簡(jiǎn)易的輸入確定的數(shù)據(jù)用于分析。同時(shí)還可以選擇用于進(jìn)一步分析的軟件模塊，帶狀記錄紙打印，自動(dòng)和控制模塊等。產(chǎn)品經(jīng)過(guò)預(yù)先設(shè)置，打開(kāi)包裝即可使用，并專(zhuān)門(mén)設(shè)計(jì)符合你的系統(tǒng)配置和數(shù)據(jù)分析要求。

• Applications:

– Evaluation of the potency of labile substances

– Determining the rates of onset and offset of drug action

– Evaluation of spasmogenic and spasmolitic agents

• Compact, allows the study of up to four tissue preparations in parallel

• Rapid removal of potentially toxic metabolites

• Obviates the necessity of repeated washing procedures

• Rates of onset and offset of drug action are easily measured

In the Coleman Superfusion Bath, the tissue is located in a horizontally split chamber. The lower part of the chamber can be swung away to simplify access to the preparation. The lower end of the tissue is held by a stainless steel hook. The thread attached to the top of the tissue passes through an opening at the top of the chamber for direct to the force transducer. The superfusion solution is fed by a multi-channel roller pump through a stainless steel cannula to the thread and it runs down the thread and superfuses the tissue. Two separate solution paths are available for superfusion with and without test substance. Two platinum wires for field stimulation are placed parallel to the tissue to form the stimulation field. The solution running down provides electrical contact between the electrodes and the tissue. The superfusion vessels are made from an acrylate block and do not require thermostating owing to the low thermal conductivity of the material used.

The superfusion chambers are mounted on a horizontal support rod according to the number of channels required. A stand for 4-position superfusion system is available. The superfusate is thermostated immediately before entering the chamber by a two line heat exchanger supplied from a water thermostat. The heat exchanger is made of a tubing coil that can be easily replaced. A collecting trough is located underneath the superfusion chambers for collecting of the used solution; alternatively the superfusate can be collected from the chamber outlet for recirculation.